Document Detail


The adverse consequences of pyoderma gangrenosum in a 13 year old child.
MedLine Citation:
PMID:  22096733     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Pyoderma gangrenosum (PG) is an uncommon, but serious, non infectious, neutrophilic dermatosis that causes cutaneous necrosis with a characteristically rapid evolution.
PRESENTATION OF CASE: A 13 year-old girl was admitted with a postoperative infected wound, which was surgically debrided. A new more aggressive lesion on the left upper extremity led the patient to the intensive care unit. Clinical diagnosis of pyoderma gangrenosum was introduced with a crucial delay. An immediate clinical improvement after immunosuppressive therapy with systemic corticosteroids and cyclosporine was observed. The extensive cutaneous deficits were covered with keratinocyte cultured cells with an aesthetically good outcome.
DISCUSSION: Diagnosis of PG in young children is very difficult, especially without dermatological evaluation. This deforming ulcerative skin disease is probably a result of altered immunologic reactivity. Its early recognition may prevent unnecessary surgical treatment which leads to dangerous complications.
CONCLUSION: To our knowledge this is the first case of PG with such a widespread distribution reported in a child, as a consequence of iatrogenic pathergy.
Authors:
Vassilis Lambropoulos; Aikaterini Patsatsi; Afroditi Tsona; Antonios Papakonstantinou; Antonios Filippopoulos; Dimitrios Sotiriadis
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Publication Detail:
Type:  Journal Article     Date:  2011-07-30
Journal Detail:
Title:  International journal of surgery case reports     Volume:  2     ISSN:  2210-2612     ISO Abbreviation:  Int J Surg Case Rep     Publication Date:  2011  
Date Detail:
Created Date:  2011-11-18     Completed Date:  2011-11-23     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101529872     Medline TA:  Int J Surg Case Rep     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  221-4     Citation Subset:  -    
Affiliation:
2 Pediatric Surgery Department, Medical School, Aristotle University of Thessaloniki, Papageorgiou Hospital, Greece.
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