Document Detail

The adenosine wedge: a new structural motif in ribosomal RNA.
MedLine Citation:
PMID:  20038632     Owner:  NLM     Status:  MEDLINE    
Here, we present a new recurrent RNA arrangement, the so-called adenosine wedge (A-wedge), which is found in three places of the ribosomal RNA in both ribosomal subunits. The arrangement has a hierarchical structure, consisting of elements previously described as recurrent motifs, namely, the along-groove packing motif, the A-minor and the hook-turn. Within the A-wedge, these elements are involved in different types of cause-effect relationships, providing together for the particular tertiary structure of the motif.
Matthieu G Gagnon; Sergey V Steinberg
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-12-28
Journal Detail:
Title:  RNA (New York, N.Y.)     Volume:  16     ISSN:  1469-9001     ISO Abbreviation:  RNA     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-25     Completed Date:  2010-02-18     Revised Date:  2010-09-28    
Medline Journal Info:
Nlm Unique ID:  9509184     Medline TA:  RNA     Country:  United States    
Other Details:
Languages:  eng     Pagination:  375-81     Citation Subset:  IM    
Departement de Biochimie, Universite de Montreal, Montreal, Quebec H3C 3J7, Canada.
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MeSH Terms
Adenosine / chemistry*
Base Sequence
Escherichia coli / chemistry,  genetics
Models, Molecular
Molecular Structure
Nucleic Acid Conformation
RNA, Bacterial / chemistry,  genetics
RNA, Ribosomal / chemistry*,  genetics
Grant Support
MOP-89923//Canadian Institutes of Health Research
Reg. No./Substance:
0/RNA, Bacterial; 0/RNA, Ribosomal; 58-61-7/Adenosine

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