Document Detail

The additive blood pressure lowering effects of exercise intensity on post-exercise hypotension.
MedLine Citation:
PMID:  20826261     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Evidence contends lower levels of physical exertion reduce blood pressure (BP) as effectively as more rigorous levels. We compared the effects of low (40% peak oxygen consumption, Vo(2)peak), moderate (60% Vo(2)peak), and vigorous (100% Vo(2)peak) exercise intensity on the BP response immediately following aerobic exercise. We also examined clinical correlates of the BP response. METHODS: Subjects were 45 men (mean +/- SEM, 43.9 +/- 1.4 years) with elevated awake ambulatory BP (ABP, 144.5 +/- 1.5/85.4 +/- 1.2 mm Hg). Men completed four randomly assigned experiments: non-exercise control and three exercise bouts at low, moderate, and vigorous intensity. All experiments began with a baseline period of seated rest. Subjects left the laboratory wearing an ABP monitor. RESULTS: Systolic ABP increased 2.8 +/- 1.6 mm Hg less after low, 5.4 +/- 1.4 mm Hg less after moderate, and 11.7 +/- 1.5 mm Hg less after vigorous than control over 9 h (P < .001). Diastolic ABP decreased 1.5 +/- 1.2 mm Hg more after low, 2.0 +/- 1.0 mm Hg more after moderate, and 4.9 +/- 1.3 mm Hg more after vigorous versus control over 9 h (P < .010). Baseline correlates of the systolic ABP post-exercise response to vigorous were fasting glucose (r = -0.415), C-reactive protein (r = -0.362), renin (r = -0.348), fasting insulin (r = 0.310), and fasting low density lipoprotein (r = -0.298) (R(2) = 0.400, P = .002). Baseline correlates of the diastolic ABP post-exercise response to vigorous were Vo(2)peak (r = -0.431), fasting low density lipoprotein (r = -0.431), renin (r = -0.411), fibrinogen (r = 0.369), and fasting glucose (r = -0.326) (R(2) = 0.429, P < .001). CONCLUSIONS: The antihypertensive effects of exercise intensity occurred in dose response fashion. Clinicians should weigh the benefits and risks of prescribing vigorous exercise intensity for those with hypertension on an individual basis.
John D Eicher; Carl M Maresh; Gregory J Tsongalis; Paul D Thompson; Linda S Pescatello
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American heart journal     Volume:  160     ISSN:  1097-6744     ISO Abbreviation:  Am. Heart J.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-09     Completed Date:  2010-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  513-20     Citation Subset:  AIM; IM    
Copyright Information:
2010 Mosby, Inc. All rights reserved.
University of Connecticut, Storrs, 06269-1110, USA.
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MeSH Terms
Blood Pressure / physiology*
Exercise / physiology*
Exercise Test
Heart Rate / physiology
Hypotension / physiopathology*
Middle Aged
Oxygen Consumption

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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