| The adaptation of megavoltage cone beam CT for use in standard radiotherapy treatment planning. | |
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MedLine Citation:
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PMID: 19287087 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Potential areas where megavoltage computed tomography (MVCT) could be used are second- and third-phase treatment planning in 3D conformal radiotherapy and IMRT, adaptive radiation therapy, single fraction palliative treatment and for the treatment of patients with metal prostheses. A feasibility study was done on using MV cone beam CT (CBCT) images generated by proprietary 3D reconstruction software based on the FDK algorithm for megavoltage treatment planning. The reconstructed images were converted to a DICOM file set. The pixel values of megavoltage cone beam computed tomography (MV CBCT) were rescaled to those of kV CT for use with a treatment planning system. A calibration phantom was designed and developed for verification of geometric accuracy and CT number calibration. The distance measured between two marker points on the CBCT image and the physical dimension on the phantom were in good agreement. Point dose verification for a 10 cm x 10 cm beam at a gantry angle of 0 degrees and SAD of 100 cm were performed for a 6 MV beam for both kV and MV CBCT images. The point doses were found to vary between +/-6.1% of the dose calculated from the kV CT image. The isodose curves for 6 MV for both kV CT and MV CBCT images were within 2% and 3 mm distance-to-agreement. A plan with three beams was performed on MV CBCT, simulating a treatment plan for cancer of the pituitary. The distribution obtained was compared with those corresponding to that obtained using the kV CT. This study has shown that treatment planning with MV cone beam CT images is feasible. |
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Authors:
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T Hannah Mary Thomas; D Devakumar; S Purnima; B Paul Ravindran |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-03-13 |
Journal Detail:
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Title: Physics in medicine and biology Volume: 54 ISSN: 0031-9155 ISO Abbreviation: Phys Med Biol Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-03-18 Completed Date: 2009-06-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401220 Medline TA: Phys Med Biol Country: England |
Other Details:
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Languages: eng Pagination: 2067-77 Citation Subset: IM |
Affiliation:
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Department of Radiotherapy, Christian Medical College, Vellore, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Cone-Beam Computed Tomography Humans Imaging, Three-Dimensional Phantoms, Imaging Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted / methods* Sensitivity and Specificity Software |
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