Document Detail

The acute effect of aerobic exercise on brachial artery endothelial function in renal transplant recipients.
MedLine Citation:
PMID:  17085983     Owner:  NLM     Status:  MEDLINE    
This study compared the effect of a 30-minute walk on brachial artery endothelial vasodilatation in kidney transplant (KT) recipients and healthy controls (HCs). Endothelial-dependent vasodilatation was measured by ultrasound before and after exercise. The HCs experienced a significant increase in vasodilatation after exercise 1 minute postocclusion when compared with the KT recipients (22%+/-13% vs 3%+/-4%; P<.05). Also, the HCs had a significantly higher vasodilatation from pre-treadmill walk to post-treadmill walk (1 minute postocclusion) when compared with KT recipients (from 3%+/-6% to 22%+/-13% vs 1%+/-3% to 3%+/-4%; P<.05). This acute vasodilatory response observed in the HCs may be related to the immediate release of nitric oxide and the combined response to shear stress and exercise. The KT recipients had several coronary artery disease risk factors that may have adversely affected endothelial function.
Ludmila M Cosio-Lima; Paul D Thompson; Katy L Reynolds; Samuel A Headley; Christa R Winter; Tina Manos; Marie A Lagasse; John R Todorovich; Michael Germain
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Preventive cardiology     Volume:  9     ISSN:  1520-037X     ISO Abbreviation:  Prev Cardiol     Publication Date:  2006  
Date Detail:
Created Date:  2006-11-06     Completed Date:  2007-04-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9813731     Medline TA:  Prev Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  211-4     Citation Subset:  IM    
Division of Health, Leisure and Exercise Science, University of West Florida, Pensacola, FL 32514-5750, USA.
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MeSH Terms
Biological Markers / blood
Brachial Artery / physiology*
Case-Control Studies
Double-Blind Method
Endothelium, Vascular / physiology*
Exercise Test
Kidney Transplantation*
Middle Aged
Time Factors
Treatment Outcome
Reg. No./Substance:
0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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