Document Detail

The active magnetic resonance imaging stent (AMRIS): initial experimental in vivo results with locally amplified MR angiography and flow measurements.
MedLine Citation:
PMID:  11606839     Owner:  NLM     Status:  MEDLINE    
RATIONALE AND OBJECTIVES: Magnetic resonance (MR) is limited by artifacts in vessels after stenting. An active MR imaging stent (AMRIS) allows for artifact-free imaging with local improvement in signal-to-noise ratio (SNR). In a rabbit model, we evaluated the imaging properties by MR angiography (MRA) and flow measurements. METHODS: The AMRIS was placed in the abdominal aorta of five rabbits. At 1.5 T, MRA (three-dimensional fast low-angle shot) was performed before and after intravenous injection of an iron oxide-based, blood-pool contrast medium (dose, 50 micromol Fe/kg), and flow measurements were performed (electrocardiographically triggered phase-contrast cine gradient-echo sequence). Mean SNRs were calculated and flow volume curves were generated. RESULTS: The SNR was 6.0 +/- 0.6 (outside the stent) versus 12.3 +/- 1.1 (inside the stent, P < 0.05) for plain MRA, 21.2 +/- 0.6 versus 40.6 +/- 5.2 (P < 0.05) for contrast-enhanced MRA, and 5.4 +/- 0.4 versus 13.7 +/- 2.1 (P < 0.05) for the magnitude images of flow measurements. Flow volume curves within and distal to the stent were comparable. CONCLUSIONS: By using the AMRIS as a vascular stent, the stented vessel segment can be examined with enhanced signal intensity on MRI.
D Kivelitz; S Wagner; J Hansel; J Schnorr; R Wetzler; M Busch; A Melzer; M Taupitz; B Hamm
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Investigative radiology     Volume:  36     ISSN:  0020-9996     ISO Abbreviation:  Invest Radiol     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2001-10-18     Completed Date:  2001-12-07     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0045377     Medline TA:  Invest Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  625-31     Citation Subset:  IM    
Institut für Radiologie, Charité, Medizinische Fakultät, Humboldt-Universität zu Berlin, Schumannstrasse 20/21, 10098 Berlin, Germnay.
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MeSH Terms
Aorta, Abdominal / pathology*,  surgery
Blood Flow Velocity
Contrast Media / administration & dosage
Ferric Compounds / diagnostic use
Ferrosoferric Oxide
Injections, Intravenous
Magnetic Resonance Angiography* / methods*
Reg. No./Substance:
0/Contrast Media; 0/Ferric Compounds; 0/superparamagnetic blood pool agent; 1317-61-9/Ferrosoferric Oxide

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