| The action of a urea-lactic acid ointment in ichthyosis with particular reference to the thickness of the horny layer. | |
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MedLine Citation:
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PMID: 943169 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of urea-lactic acid ointment on the scales of ichthyotic skin was assessed using the 'cell swelling' technique of Christophers & Kligman. The thickness of the horny layer and of the scales was reduced both by the ointment and by the base. The formation of scales was shown to differ from that in psoriasis where the scale forms at the apex of th a rete peg and is symmetrical whereas in ichthyosis the separation of the scale may be at an entirely different depth at one margin. There is an increase in the number of 'T' cells in X-linked recessive ichthyosis. |
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Authors:
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C Blair |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: The British journal of dermatology Volume: 94 ISSN: 0007-0963 ISO Abbreviation: Br. J. Dermatol. Publication Date: 1976 Feb |
Date Detail:
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Created Date: 1976-06-02 Completed Date: 1976-06-02 Revised Date: 2006-09-18 |
Medline Journal Info:
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Nlm Unique ID: 0004041 Medline TA: Br J Dermatol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 145-53 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Female Humans Ichthyosis / drug therapy*, pathology Lactates / pharmacology, therapeutic use* Male Middle Aged Ointment Bases / pharmacology Psoriasis / pathology Skin / drug effects, pathology Tretinoin / therapeutic use Urea / pharmacology, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Lactates; 0/Ointment Bases; 302-79-4/Tretinoin; 57-13-6/Urea |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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