| Is acid relevant in the genesis of dyspeptic symptoms associated with nonerosive reflux disease? | |
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MedLine Citation:
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PMID: 18334866 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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[table: see text] A consistent subset of patients with NERD suffers from symptoms centered in the upper part of the abdomen that are more characteristic of functional dyspepsia than reflux disease. The cause of this overlap is still unclear, but acid has been implicated as one of the possible common pathophysiological factors responsible for these two categories of upper gastrointestinal (GI) symptoms. Many physiological investigations and the modest success of proton pump inhibitors in resolving dyspeptic symptoms associated with typical reflux syndrome seem to support the concept that functional dyspepsia and NERD are two separate entities, which need to be treated with different drugs. |
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Authors:
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Vincenzo Savarino; Edoardo Savarino |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: European journal of gastroenterology & hepatology Volume: 20 ISSN: 0954-691X ISO Abbreviation: Eur J Gastroenterol Hepatol Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-03-12 Completed Date: 2008-07-24 Revised Date: 2009-10-16 |
Medline Journal Info:
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Nlm Unique ID: 9000874 Medline TA: Eur J Gastroenterol Hepatol Country: England |
Other Details:
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Languages: eng Pagination: 252-4 Citation Subset: IM |
Affiliation:
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Gastrointestinal Unit, University of Genova, Genova, Italy. vsavarin@unige.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dyspepsia
/
drug therapy,
etiology*,
therapy Esophageal pH Monitoring / instrumentation Female Gastric Acid / physiology, secretion* Gastroesophageal Reflux / complications*, drug therapy Humans Male Proton Pump Inhibitors / therapeutic use* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Proton Pump Inhibitors |
| Comments/Corrections | |
Comment On:
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Eur J Gastroenterol Hepatol. 2008 Apr;20(4):264-8
[PMID:
18334868
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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