| The accuracy of computed tomographic perfusion in detecting recurrent nasopharyngeal carcinoma after radiation therapy. | |
| | |
MedLine Citation:
|
PMID: 21150454 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
OBJECTIVES: : To assess the diagnostic accuracy of computed tomographic (CT) perfusion technique in discriminating recurrent nasopharyngeal carcinoma (NPC) after radiation therapy. METHODS: : Forty-eight patients with a pathologic finding as reference standards were divided into 2 groups, recurrent and nonrecurrent NPCs. Perfusion parameters blood flow (BF), blood volume (BV), permeability surface (PS), and mean transit time were statistically analyzed. A receiver operating characteristic curve was used to study whether CT perfusion parameters could aid in detecting recurrent NPC. RESULTS: : Blood flow, BV, and PS values between recurrent NPC (n = 27) and nonrecurrent NPC (n = 21) were 526.8 (168.1) versus 312.1 (214.4) mL/100 g per minute, 35.1 (23.6) versus 9.2 (8.0) (ml/100 g), and 53.4 (34.3) versus 17.6 (14.7) mL/100 g per minute, respectively. There was a significant difference between these 2 groups (P < 0.01). Mean transit time values in these 2 groups were 3.5 (2.0) versus 4.3 (2.7) seconds; there was no statistical difference. To optimize sensitivity and specificity, BF, BV, and PS threshold values for differentiating between recurrent and nonrecurrent NPCs were 537.20 mL/100 g per minute, 37.18 (ml/100 g), and 57.34 mL/100 g per minute, respectively. According to threshold values of BF, BV, and PS, sensitivity and specificity for distinguishing recurrent and nonrecurrent NPCs were 92.6% and 76.2%, 96.3% and 81%, and 81.5% and 61.9%, respectively. CONCLUSIONS: : The CT perfusion technique may be helpful to find patients with recurrent NPC after radiation therapy. |
| | |
Authors:
|
Guanqiao Jin; Danke Su; Lidong Liu; Xuna Zhu; Dong Xie; Wei Zhao |
Related Documents
:
|
21434 - Oxygen affinity of avian blood. 9848734 - In vivo correlation between blood t2* and oxygen saturation. 8884624 - Validation of transcranial near-infrared spectroscopy for evaluation of cerebral blood ... 9445334 - Blood flow of the middle cerebral artery with sleep-disordered breathing: correlation w... 16337824 - Altering end-to-side anastomosis junction hemodynamics: the effects of flow-splitting. 2399874 - Chemiluminescence and chemotaxis assay of canine granulocytes: a methodological study. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of computer assisted tomography Volume: 35 ISSN: 1532-3145 ISO Abbreviation: J Comput Assist Tomogr Publication Date: 2011 Jan-Feb |
Date Detail:
|
Created Date: 2011-01-19 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7703942 Medline TA: J Comput Assist Tomogr Country: United States |
Other Details:
|
Languages: eng Pagination: 26-30 Citation Subset: IM |
Affiliation:
|
From the Department of Radiology, Oncology Hospital, Guangxi Medical University, Nanning, People's Republic of China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Evaluation of the Relationship Between L5-S1 Spondylolysis and Isthmic Spondylolisthesis and Lumbosa...
Next Document: Neuromyelitis Optica Antibodies in Patients With Severe Optic Neuritis in China.