| The accuracy of EUS and helical CT in the assessment of vascular invasion by peripapillary malignancy. | |
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MedLine Citation:
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PMID: 11174289 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The relative accuracy of helical CT and EUS for defining the local resectability of peripapillary malignancies is undefined. METHODS: Fifty-one patients with a peripapillary malignancy and no metastatic disease were prospectively evaluated with helical CT and EUS. Imaging results were compared with surgical staging, and a tumor was defined as resectable when there was no macroscopic or microscopic residual tumor. RESULTS: Nine patients had surgically confirmed locally unresectable disease, which was accurately predicted by EUS in 6 patients (sensitivity 67%) and by helical CT in 3 patients (sensitivity 33%; p = 0.35). When only patients with complete EUS examinations were included, the sensitivities of EUS and helical CT for vascular invasion were 100% and 33% (p = 0.06), respectively. When all patients not undergoing surgery because of imaging evidence of locally unresectable disease were included, the sensitivities were 100% and 62.5% (p = 0.02), respectively. One of 15 patients with a tumor amenable to surgical resection was labeled as unresectable by EUS but subsequently had a local recurrence of the tumor. The specificities of EUS (93%) and helical CT (100%) were similar. CONCLUSION: EUS is more sensitive than helical CT for detecting vascular invasion by peripapillary malignancies and should be added to staging protocols, particularly when findings on helical CT are equivocal. |
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Authors:
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W M Tierney; I R Francis; F Eckhauser; G Elta; T T Nostrant; J M Scheiman |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Gastrointestinal endoscopy Volume: 53 ISSN: 0016-5107 ISO Abbreviation: Gastrointest. Endosc. Publication Date: 2001 Feb |
Date Detail:
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Created Date: 2001-02-22 Completed Date: 2001-06-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0010505 Medline TA: Gastrointest Endosc Country: United States |
Other Details:
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Languages: eng Pagination: 182-8 Citation Subset: IM |
Affiliation:
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Department of Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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diagnosis*,
secondary* Adult Aged Aged, 80 and over Ampulla of Vater* Common Bile Duct Neoplasms / diagnosis* Endosonography* Female Humans Male Middle Aged Pancreatic Neoplasms / diagnosis* Predictive Value of Tests Prospective Studies Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed* Vascular Neoplasms / diagnosis*, secondary* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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