Document Detail


The acceptability of an injectable, once-a-month male contraceptive in China.
MedLine Citation:
PMID:  16627044     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: An acceptability study of an injectable preparation of the synthetic steroid testosterone undecanoate as a once-a-month male contraceptive method was carried out concurrently with, but independently from, a clinical safety and efficacy trial of this preparation in China, from 1997 to 1999. METHOD: Three hundred eight men, the entire group of volunteers enrolled in the clinical trial, were interviewed using a structured questionnaire. In addition, 24 sessions of focus group discussions and 54 in-depth interviews were conducted with a broad range of stakeholders, including men enrolled in the trial and their wives, potential users, service providers, principal investigators of the six participating clinical trial centers, provincial and national policy makers, and experts engaged in research and development of male methods of contraception. RESULTS: Overall, men found the regimen to be acceptable, and most reported no change or an improvement in their well-being as a result of participating in the clinical study. The frequency of the injections, monthly semen analyses and the need to use another contraceptive method during the period of sperm suppression were reported inconveniences of the trial. CONCLUSION: Further research is needed to assess the long-term safety, continuation rates, satisfaction among users and issues related to service delivery.
Authors:
Liying Zhang; Iqbal H Shah; Yunrong Liu; Kirsten M Vogelsong; Lihong Zhang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-01-20
Journal Detail:
Title:  Contraception     Volume:  73     ISSN:  0010-7824     ISO Abbreviation:  Contraception     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-04-21     Completed Date:  2006-10-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0234361     Medline TA:  Contraception     Country:  United States    
Other Details:
Languages:  eng     Pagination:  548-53     Citation Subset:  IM    
Affiliation:
National Research Institute for Population and Family Planning, Research Center of Social Medicine, Beijing 100081, China. lyzhang63@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Antispermatogenic Agents* / administration & dosage,  adverse effects
Attitude
China
Communication
Decision Making
Female
Humans
Injections
Male
Motivation
Patient Acceptance of Health Care*
Testosterone / administration & dosage,  adverse effects,  analogs & derivatives*
Chemical
Reg. No./Substance:
0/Antispermatogenic Agents; 58-22-0/Testosterone; 5949-44-0/testosterone undecanoate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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