Document Detail


The absence of strand-specific repair for the DNA polymerase pol gene in Deinococcus radiodurans.
MedLine Citation:
PMID:  9713687     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Deinococcus radiodurans is characterized by its extreme resistance to ionizing radiation. Although Mn+2 was taken up by the cells at a high speed, the absorption of Mn+2 by the cells did not affect their survival rate when irradiated by UV light. However, the Mn-induced-cell-division (Mn-CD) cells do lose their resistance to UV radiation. This can be explained by the fact that the Mn-CD cells were less efficient to remove pyrimidine dimers on damaged DNA. We also found that there is no strand-specific repair of the pol gene in this organism.
Authors:
C S Lin; H C Wang; T Y Wong; J K Liu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biochemistry and molecular biology international     Volume:  45     ISSN:  1039-9712     ISO Abbreviation:  Biochem. Mol. Biol. Int.     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-10-19     Completed Date:  1998-10-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9306673     Medline TA:  Biochem Mol Biol Int     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  651-62     Citation Subset:  IM    
Affiliation:
Department of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, ROC.
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MeSH Terms
Descriptor/Qualifier:
DNA Damage
DNA Repair*
DNA, Bacterial / metabolism
DNA-Directed DNA Polymerase / genetics*
Genes, Bacterial
Gram-Positive Cocci / enzymology,  genetics*,  radiation effects
Manganese / metabolism,  pharmacology
Pyrimidine Dimers / metabolism
Ultraviolet Rays
Chemical
Reg. No./Substance:
0/DNA, Bacterial; 0/Pyrimidine Dimers; 7439-96-5/Manganese; EC 2.7.7.7/DNA-Directed DNA Polymerase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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