| The absence of strand-specific repair for the DNA polymerase pol gene in Deinococcus radiodurans. | |
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MedLine Citation:
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PMID: 9713687 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Deinococcus radiodurans is characterized by its extreme resistance to ionizing radiation. Although Mn+2 was taken up by the cells at a high speed, the absorption of Mn+2 by the cells did not affect their survival rate when irradiated by UV light. However, the Mn-induced-cell-division (Mn-CD) cells do lose their resistance to UV radiation. This can be explained by the fact that the Mn-CD cells were less efficient to remove pyrimidine dimers on damaged DNA. We also found that there is no strand-specific repair of the pol gene in this organism. |
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Authors:
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C S Lin; H C Wang; T Y Wong; J K Liu |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biochemistry and molecular biology international Volume: 45 ISSN: 1039-9712 ISO Abbreviation: Biochem. Mol. Biol. Int. Publication Date: 1998 Jul |
Date Detail:
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Created Date: 1998-10-19 Completed Date: 1998-10-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9306673 Medline TA: Biochem Mol Biol Int Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 651-62 Citation Subset: IM |
Affiliation:
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Department of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, ROC. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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DNA Damage DNA Repair* DNA, Bacterial / metabolism DNA-Directed DNA Polymerase / genetics* Genes, Bacterial Gram-Positive Cocci / enzymology, genetics*, radiation effects Manganese / metabolism, pharmacology Pyrimidine Dimers / metabolism Ultraviolet Rays |
| Chemical | |
Reg. No./Substance:
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0/DNA, Bacterial; 0/Pyrimidine Dimers; 7439-96-5/Manganese; EC 2.7.7.7/DNA-Directed DNA Polymerase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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