Document Detail

aEEG and NIRS during transition and resuscitation after birth: promising additional tools; an observational study.
MedLine Citation:
PMID:  23313424     Owner:  NLM     Status:  Publisher    
AIM OF THE STUDY: During resuscitation no routine cerebral monitoring is available. We aimed at monitoring cerebral activity and oxygenation continuously during neonatal transition and resuscitation. METHODS: Neonates >34 weeks of gestation born via caesarean section were included. Cerebral activity was continuously measured with amplitude-integrated-EEG (aEEG) and cerebral oxygenation (rSO2) with near-infrared-spectroscopy (NIRS) during the first ten minutes after birth. For quantitative analysis of aEEG every minute the mean minimum amplitude (Vmin) and maximum amplitude (Vmax) was determined. Uncompromised neonates were compared to neonates in need of resuscitation. RESULTS: Out of 224 eligible neonates 31 uncompromised and 15 in need of respiratory support were included. Uncompromised neonates showed higher values for Vmin in the third minute and higher values for Vmax in the third and fourth minute compared to the tenth minute post partum. In uncompromised neonates rSO2 values during the first six minutes after birth were lower compared to minute ten. Neonates in need of respiratory support had lower rSO2 values over the first eight minutes after birth compared to minute ten. CONCLUSIONS: This is the first study demonstrating that monitoring of aEEG and NIRS to measure cerebral activity and oxygenation during immediate postpartum transition is feasible. During transition compromised neonates requiring resuscitation showed a different cerebral activity pattern compared to uncompromised neonates.
Gerhard Pichler; Alexander Avian; Corinna Binder; Heinz Zotter; Georg Marcus Schmölzer; Nicholas Morris; Wilhelm Müller; Berndt Urlesberger
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-8
Journal Detail:
Title:  Resuscitation     Volume:  -     ISSN:  1873-1570     ISO Abbreviation:  Resuscitation     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0332173     Medline TA:  Resuscitation     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013. Published by Elsevier Ireland Ltd.
Research Unit for Cerebral Development and Oximetry, Division of Neonatology, Department of Pediatrics, Medical University of Graz, Austria. Electronic address:
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