| Zygomycosis presenting as acute myocardial infarction during hematological malignancies. | |
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MedLine Citation:
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PMID: 18451576 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Here we report two patients with hematological malignancies associated with complications of fatal cardiac zygomycosis. The first case, a 72-year-old man with myelodysplastic syndrome being treated with low-dose cytarabine, died of sudden cardiac arrest. An autopsy revealed disseminated zygomycosis accompanied with occlusion of the coronary artery by fungal thrombi. The second case, a 52-year-old woman with acute lymphoblastic leukemia, developed febrile neutropenia and skin eruptions with induration on the face and extremities during the first induction chemotherapy. She experienced sudden bradycardia with unstable hemodynamics and died of acute myocardial infarction. Histological examination of a skin biopsy demonstrated zygomycosis. In light of the above, it should be kept in mind that cardiac zygomycosis might occur in hematologically compromised patients presenting with acute myocardial infarction. |
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Authors:
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Satoru Joshita; Kiyoshi Kitano; Tadanobu Nagaya; Atsushi Kamijo; Koh Nakazawa; Fumihiro Ishida |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-05-01 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 47 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2008 |
Date Detail:
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Created Date: 2008-05-02 Completed Date: 2008-06-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 839-42 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Matsumoto National Hospital, Matsumoto. joshita@hsp.md.shinshu-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Coronary Vessels / microbiology*, pathology Female Humans Immunocompromised Host Male Middle Aged Myelodysplastic Syndromes / immunology, microbiology* Myocardial Infarction / etiology* Precursor Cell Lymphoblastic Leukemia-Lymphoma / immunology, microbiology* Zygomycosis / complications*, pathology |
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