Document Detail


Zygomycosis in the immunocompromised patient: a case report.
MedLine Citation:
PMID:  16918059     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Zygomycosis is a highly aggressive infection observed in immunocompromised patients, such as those with haematological malignancies. The sites most frequently involved are the sinuses and the lungs. New diagnostic tools and new antifungal treatments are essential in order to diagnose early and treat efficiently infections due to moulds. We report a case of sinusitis due to Absidia corymbifera occurring during chemotherapy-induced bone marrow aplasia in a patient with acute leukaemia. The sinusitis was successfully treated with AmBisome, and surgical debridement.
Authors:
Aspasia Georgala; Marc Vekemans; Mireille Husson; Nathalie Meuleman; Hugues Beguin; Nicole Nolard; Mickael Aoun
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta bio-medica : Atenei Parmensis     Volume:  77 Suppl 2     ISSN:  0392-4203     ISO Abbreviation:  -     Publication Date:  2006  
Date Detail:
Created Date:  2006-08-21     Completed Date:  2006-12-04     Revised Date:  2008-09-25    
Medline Journal Info:
Nlm Unique ID:  101295064     Medline TA:  Acta Biomed     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  5-9     Citation Subset:  IM    
Affiliation:
Infectious Disease Department, Jules Bordet Institute, Brussels, Belgium. nathalie.cardinal@bordet.be
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MeSH Terms
Descriptor/Qualifier:
Absidia / isolation & purification*
Acute Disease
Aerosols
Amphotericin B / administration & dosage,  therapeutic use*
Amsacrine / administration & dosage
Antibiotic Prophylaxis
Antifungal Agents / administration & dosage,  therapeutic use*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Combined Modality Therapy
Cytarabine / administration & dosage
Daunorubicin / administration & dosage
Debridement
Drug Resistance, Fungal
Drug Resistance, Neoplasm
Etoposide / administration & dosage
Fluconazole / therapeutic use
Humans
Immunocompromised Host
Leukemia / complications,  drug therapy
Liposomes
Middle Aged
Mucormycosis / drug therapy*,  microbiology,  surgery
Sinusitis / drug therapy*,  microbiology,  radiography,  surgery
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Aerosols; 0/Antifungal Agents; 0/Liposomes; 0/liposomal amphotericin B; 1397-89-3/Amphotericin B; 147-94-4/Cytarabine; 20830-81-3/Daunorubicin; 33419-42-0/Etoposide; 51264-14-3/Amsacrine; 86386-73-4/Fluconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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