| Zygomatico-orbital intra-arterial melphalan infusion for intraocular retinoblastoma. | |
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MedLine Citation:
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PMID: 21990490 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Retinoblastoma is a rare and curable malignancy affecting the pediatric population. For advanced stage intraocular retinoblastoma, enucleation remains the primary treatment modality, although the use of laser photocoagulation, cryotherapy, radiotherapy and chemotherapy are frequently used, particularly in the setting of bilateral disease. Intravenous chemotherapy is the long-standing method of delivery, but local administration (subtenon, intravitreal or intra-arterial) is gaining in popularity because of the reduced side effects related to systemic administration. Of these newer methods, intra-arterial infusion has demonstrated technical feasibility, few procedural complications and robust tumor response. A case is described where a collateral supply to the affected ophthalmic artery was via the zygomatico-orbital branch of the ipsilateral superficial temporal artery. Melphalan infusion was performed via this pathway without incident. |
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Authors:
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Daniel Cooke; Hamed Farid; Warren Kim; Christopher Dowd; Randall Higashida; Van Halbach |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-11 |
Journal Detail:
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Title: Journal of neurointerventional surgery Volume: - ISSN: 1759-8486 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-10-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101517079 Medline TA: J Neurointerv Surg Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Radiology and Biomedical Imaging, University California San Francisco, San Francisco, California, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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