| Zotepine in Huntington's disease. | |
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MedLine Citation:
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PMID: 12672176 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The authors report a patient with Huntington's disease (HD) presenting with severe chorea. The motor scale of the unified HD rating scale (UHDRS-I) revealed 81 points. Motor function clearly improved with zotepine, until she reached an UHDRS-I of 34 points on day 7 of treatment. The patient was stable for at least 12 weeks. The improvement includes all seven categories of the UHDRS-I, especially chorea, gait and oral function. This is the first description of zotepine in HD. Our findings suggest that zotepine is useful in the treatment of HD chorea. Controlled trials of its use in HD would be welcome. |
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Authors:
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Raphael M Bonelli; Gerald Niederwieser; Theresa Lahousen; Peter Hofmann |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Human psychopharmacology Volume: 18 ISSN: 0885-6222 ISO Abbreviation: Hum Psychopharmacol Publication Date: 2003 Apr |
Date Detail:
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Created Date: 2003-04-02 Completed Date: 2003-08-22 Revised Date: 2008-03-06 |
Medline Journal Info:
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Nlm Unique ID: 8702539 Medline TA: Hum Psychopharmacol Country: England |
Other Details:
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Languages: eng Pagination: 227-9 Citation Subset: IM |
Copyright Information:
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Copyright 2003 John Wiley & Sons, Ltd. |
Affiliation:
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Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Bergstrasse 27, A-8021 Graz, Austria. rm.bonelli@nextra.at |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antipsychotic Agents / therapeutic use* Chorea / drug therapy Dibenzothiepins / therapeutic use* Female Humans Huntington Disease / drug therapy* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 0/Dibenzothiepins; 26615-21-4/zotepine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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