Document Detail


Zoonotic helminth infections of humans: echinococcosis, cysticercosis and fascioliasis.
MedLine Citation:
PMID:  17762782     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE OF REVIEW: Tissue parasites of humans are still prevalent in most regions of the world, and are also seen more frequently in developed countries due to increasing travel patterns. In particular, Echinococcus infections still account for hepatic and pulmonary pathology, cysticercosis is a major cause of seizures and epilepsy, and fascioliasis also causes significant liver pathology. This review summarizes current knowledge on clinical and epidemiologic aspects of zoonotic disease caused by tissue helminths. RECENT FINDINGS: Tissue helminth infections remain as a public health concern. Recent research has provided new insights into clinical disease in humans and improved methods for diagnosis, treatment and control, arising mostly from the application of new techniques for immune and molecular diagnosis, availability of data from controlled trials, and development of new vaccines. Specific antiparasitic therapies are now better characterized, and new control tools are available. SUMMARY: Recent research has provided new diagnostic technologies applicable to diagnosis, treatment and control, but effective interventions to reduce transmission are rarely applied. Despite some progress in their control, these zoonoses continue to be a major public health problem in many regions both in developing countries and in some more developed ones.
Authors:
Hector H Garcia; Pedro L Moro; Peter M Schantz
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current opinion in infectious diseases     Volume:  20     ISSN:  0951-7375     ISO Abbreviation:  Curr. Opin. Infect. Dis.     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-08-31     Completed Date:  2007-12-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809878     Medline TA:  Curr Opin Infect Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  489-94     Citation Subset:  IM    
Affiliation:
Department of Microbiology, School of Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru. hgarcia@jhsph.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Cysticercosis* / diagnosis,  prevention & control,  therapy
Echinococcosis* / diagnosis,  epidemiology,  prevention & control,  therapy
Echinococcus / physiology
Fasciola / physiology
Fascioliasis* / diagnosis,  epidemiology,  prevention & control,  therapy
Humans
Taenia solium / physiology
Zoonoses
Grant Support
ID/Acronym/Agency:
//Wellcome Trust

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