Document Detail


"Zone of avoidance": RR interval distribution in tachograms, histograms, and Poincaré plots of a Boxer dog.
MedLine Citation:
PMID:  21036115     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The RR intervals of sinus and ventricular beats were determined by analysis of a 24-h ambulatory electrocardiogram in a Boxer before and after treatment with sotalol. These RR intervals were plotted using tachograms, histograms, and Poincaré plots. The tachogram demonstrated a 'band' wherein a range of RR intervals was infrequent, the histogram did not take the form of a single Gaussian distribution of RR intervals, and the Poincaré plot showed nonhomogeneous beat-to-beat variability. This type of patterning was described as a "zone of avoidance" potentially caused by the clustering of beats within specific ranges. Treatment with sotalol enhanced the "zone of avoidance". Further investigation is needed to understand the mechanism for this observation as well as any clinical implications.
Authors:
N Sydney Moïse; Andrea Gladuli; Shari A Hemsley; Niels F Otani
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-10-29
Journal Detail:
Title:  Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology     Volume:  12     ISSN:  1875-0834     ISO Abbreviation:  J Vet Cardiol     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-06     Completed Date:  2011-03-18     Revised Date:  2014-09-13    
Medline Journal Info:
Nlm Unique ID:  101163270     Medline TA:  J Vet Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  191-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier B.V. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Arrhythmia Agents / therapeutic use
Arrhythmia, Sinus / diagnosis,  drug therapy,  physiopathology,  veterinary*
Dog Diseases / diagnosis,  drug therapy,  physiopathology*
Dogs
Electrocardiography, Ambulatory / veterinary
Female
Sotalol / therapeutic use
Grant Support
ID/Acronym/Agency:
R01 HL089271/HL/NHLBI NIH HHS; R01 HL089271-03/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents; A6D97U294I/Sotalol
Comments/Corrections

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