Document Detail

Zollinger Ellison syndrome, treated with lansoprazole, during pregnancy.
MedLine Citation:
PMID:  17318560     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Zollinger Ellison syndrome (ZES), an ulcerative disease of the upper gastrointestinal tract that involves the production of high levels of gastrin and gastric acid, is a rare, symptomatic, endocrine neoplastic disease. CASE: We report a rare case of gastrinoma that was first diagnosed during pregnancy in which the primary tumor was located in the liver. The ZES was well controlled with Zoton (Lansoprazole) following surgery. The patient had an uneventful pregnancy and delivery without significant complications. CONCLUSIONS: The present case suggests that treatment with Zoton for ZES during pregnancy is safe and effective.
Amit Mayer; Eyal Sheiner; Gershon Holcberg
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  276     ISSN:  0932-0067     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-12-17     Completed Date:  2008-01-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  171-3     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, P.O. Box 151, Beer-Sheva 84101, Israel.
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MeSH Terms
2-Pyridinylmethylsulfinylbenzimidazoles / therapeutic use*
Anti-Ulcer Agents / therapeutic use*
Gastrinoma / complications*,  drug therapy,  pathology,  surgery
Gastrins / blood
Infant, Newborn
Pregnancy Complications, Neoplastic / blood,  drug therapy*,  surgery
Pregnancy Outcome
Zollinger-Ellison Syndrome / blood,  complications,  drug therapy*,  surgery
Reg. No./Substance:
0/2-Pyridinylmethylsulfinylbenzimidazoles; 0/Anti-Ulcer Agents; 0/Gastrins; 103577-45-3/lansoprazole

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