Document Detail

Zinc status in infantile wheezing.
MedLine Citation:
PMID:  16703575     Owner:  NLM     Status:  MEDLINE    
The increase in prevalence of asthma is strongly dependent on environmental factors, including diet. Significant decreases in the intake of dietary zinc may be an important contributing factor to the increasing incidence of wheezing and asthma, but there have been no studies evaluating zinc levels in wheezy infants. Our objective was to investigate the zinc status of wheezy infants. Wheezy infants (n = 34) and healthy children (n = 14) were included in the study. Total IgE and eosinophil counts were obtained, and skin testing was done with a battery of 25 antigens with appropriate positive and negative controls. Levels of zinc were determined in hair, using a Polarized Zeeman Atomic Absorption Spectrophotometer (Hitachi Z-800). No significant difference was observed in peripheral blood eosinophil counts and total IgE levels among groups (P > 0.05). Hair zinc levels were significantly lower in wheezy infants (P < 0.001). In conclusion, hair zinc levels were lower in wheezy infants than in healthy controls, suggesting that zinc deficiency may influence the risk of wheezing in early childhood.
Fulya Tahan; Cigdem Karakukcu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric pulmonology     Volume:  41     ISSN:  8755-6863     ISO Abbreviation:  Pediatr. Pulmonol.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-05-31     Completed Date:  2007-02-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8510590     Medline TA:  Pediatr Pulmonol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  630-4     Citation Subset:  IM    
Department of Pediatric Allergy, Erciyes University School of Medicine, Kayseri, Turkey.
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MeSH Terms
Child, Preschool
Hair / chemistry*
Respiratory Sounds / etiology*
Zinc / analysis*
Reg. No./Substance:

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