| Zinc regulation of food intake: new insights on the role of neuropeptide Y. | |
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MedLine Citation:
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PMID: 12918877 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The role of neuropeptide Y (NPY) in feeding behavior and zinc deficiency-induced anorexia has been controversial because hypothalamic NPY levels are elevated in both zinc deficiency and food restriction. A recent report shows that while NPY is released from terminals in the paraventricular nucleus of the hypothalamus of food-restricted animals, this release is significantly impaired in zinc-deficient animals. Zinc deficiency may therefore cause anorexia by inhibiting the release of NPY that is required for receptor activation. |
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Authors:
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Cathy W Levenson |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Nutrition reviews Volume: 61 ISSN: 0029-6643 ISO Abbreviation: Nutr. Rev. Publication Date: 2003 Jul |
Date Detail:
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Created Date: 2003-08-15 Completed Date: 2003-08-26 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0376405 Medline TA: Nutr Rev Country: United States |
Other Details:
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Languages: eng Pagination: 247-9 Citation Subset: IM |
Affiliation:
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Florida State University, Program in Neuroscience, Department of Nutrition, Food & Exercise Sciences, 237 Biomedical Research Facility, Tallahassee, FL 32306-4340, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Animals Anorexia Nervosa / drug therapy, metabolism* Eating / drug effects* Female Humans Male Neuropeptide Y / metabolism, physiology* Rats Zinc / deficiency*, metabolism, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Neuropeptide Y; 7440-66-6/Zinc |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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