Document Detail


Zinc promotes the phototoxic effect of blue light against malodour producing bacteria in an experimental oral biofilm.
MedLine Citation:
PMID:  24913560     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Oral malodour is considered to be caused mainly by the production of volatile sulfide compounds (VSC) by anaerobic Gram-negative oral bacteria. Previous study showed that these bacteria were susceptible to blue light (wavelengths of 400- 500 nm). In the present study, we tested the effect of blue light in the presence of zinc and erythrosin on malodour production in an experimental oral biofilm. Biofilms were exposed to a plasma-arc light source for 30, 60, and 120 sec (i.e. fluences of 41, 82, and 164 J/cm2, respectively) with or without the addition of zinc acetate and erythrosin B. Following light exposure biofilm samples were examined for malodour production (Odour judge), VSC production (HalimeterTM), and VSC producing bacteria quantification using light microscopy (MSA) and in-situ confocal laser scanning microscopy (CLSM). Results showed that the exposure of experimental oral biofilm to blue light in the presence of zinc caused an increased reduction in malodour production concomitant with a reduction in VSC producing bacteria population. These results suggest that zinc promotes blue light phototoxicity against malodour producing bacteria.
Authors:
Nir Sterer; Uziel Jeffet; Aurel Dadoun; Ronit Bar-Ness Greenstein; David Kohavi
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-9
Journal Detail:
Title:  Journal of medical microbiology     Volume:  -     ISSN:  1473-5644     ISO Abbreviation:  J. Med. Microbiol.     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0224131     Medline TA:  J Med Microbiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014, the Society for General Microbiology.
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