Document Detail


Zinc in mammalian sperm: a review.
MedLine Citation:
PMID:  6378991     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The relationship of zinc to morphologic, physiologic, and metabolic functions in the male reproductive system are summarized, and gaps in current understanding are pointed out. Semen and its constituents generally contain high zinc, although concentrations vary among animals and species; the relationships between zinc and fertility of semen is unclear. During zinc deficiency, retarded development of testicular growth involved marked atrophy of tubular epithelium and reduced deoxyribonucleic acid, ribonucleic acid, and protein, as well as reduced zinc contents of testis, epididymis, and dorsolateral prostate. Functions of zinc in hormone interrelationships are little understood, but zinc deficiency decreases output of pituitary gonadotrophins and androgen production, and zinc turnover involves testosterone as well as pituitary hormones. Metabolic regulation of sperm appears to be mediated through zinc as a regulator of enzyme activity in the semen. Within spermatozoa, zinc is closely associated with sulfhydryl groups and disulfide linkages and is concentrated in the tail. Control of motility of sperm by zinc apparently involves control of energy utilization through adenosine triphosphate systems involved in contraction and through regulation of phospholipid energy reserves. The many roles for zinc in the male reproductive system are extremely complex and scarcely understood. The importance of zinc contents of commonly utilized feedstuffs in relation to reproductive capabilities of the mammalian sperm remain unclear, although zinc deficiency in relation to male reproduction may be much more widespread than is recognized commonly.
Authors:
M Hidiroglou; J E Knipfel
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Journal of dairy science     Volume:  67     ISSN:  0022-0302     ISO Abbreviation:  J. Dairy Sci.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-09-07     Completed Date:  1984-09-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985126R     Medline TA:  J Dairy Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1147-56     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cattle
Fertility
Humans
Male
Mammals* / physiology
Semen / analysis
Species Specificity
Sperm Motility
Spermatozoa / analysis*,  metabolism
Swine
Testis / growth & development,  physiology
Zinc / analysis*,  deficiency,  metabolism,  physiology
Chemical
Reg. No./Substance:
7440-66-6/Zinc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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