Document Detail


Zinc concentrations in maternal blood during pregnancy and post partum, in cord blood and amniotic fluid.
MedLine Citation:
PMID:  3439449     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Zinc deficiency was reported to lead to congenital malformations and abnormal fetal development, and zinc concentration in amniotic fluid has been found to be correlated with fetal birth weight. In the present study, zinc concentrations were estimated in 8 pregnant women at 15 gestational weeks and 68 pregnant women at term. Maternal serum zinc concentration in early and term pregnancy was significantly lower than that of the non-pregnant controls (mean values +/- SEM being 9.8 +/- 0.6, 9.3 +/- 0.2, and 11.5 +/- 0.3 mumol/l, respectively). Maternal serum zinc concentrations reached the non-pregnant level by one week post partum. The mean serum zinc concentration in cord blood was 14.4 (+/- 0.4) mumol/l. The zinc concentration in the amniotic fluid was very low both in early pregnancy and at term 1.1 and 0.8 mumol/l, respectively, and no correlation was found to the birth weight. Low serum zinc content in pregnant women occurs as a normal feature and congenital malformation as a consequence of disturbed zinc metabolism is probably only to be seen in instances of extreme zinc deficiency in conjunction with malnutrition.
Authors:
K Marsál; S Furgyik
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  66     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1987  
Date Detail:
Created Date:  1988-04-06     Completed Date:  1988-04-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  653-6     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, Malmö General Hospital, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amniotic Fluid / metabolism*
Female
Fetal Blood / metabolism*
Humans
Infant, Newborn
Labor, Obstetric / blood
Postpartum Period / blood*
Pregnancy / blood*
Pregnancy Trimester, First
Zinc / blood,  metabolism*
Chemical
Reg. No./Substance:
7440-66-6/Zinc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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