Document Detail

Zinc intake and the risk of hyperglycemia among Chinese adults: the prospective Jiangsu Nutrition Study (JIN).
MedLine Citation:
PMID:  20306008     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To prospectively examine the associations between zinc intake, the zinc to heme iron ratio and the incidence of hyperglycemia in Chinese.
METHODS: We followed 1056 healthy adults aged 20 and older from 2002 to 2007. Dietary data were collected using 3-day food record and food frequency questionnaire. Hyperglycemia was defined as fasting plasma glucose > 5.6 mmol/l.
RESULTS: During the 5 years of follow-up, we documented 125 incident cases of hyperglycemia. Zinc intake alone was not associated with the risk of hyperglycemia. The zinc to heme iron ratio was inversely associated with the risk of hyperglycemia: odds ratios (OR, 95% CI) across increasing quartiles of the zinc to heme iron ratio were 1.00, 0.78(0.44-1.37), 0.40(0.19-0.83), and 0.21(0.08-0.54)(p for trend= 0.001). Adjustment for lifestyle covariates did not significantly change the associations.
CONCLUSIONS: This cohort study suggests that the zinc to heme iron intake ratio was significantly associated with a decreased risk of hyperglycemia in Chinese adults.
Z Shi; B Yuan; L Qi; Y Dai; H Zuo; M Zhou
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The journal of nutrition, health & aging     Volume:  14     ISSN:  1760-4788     ISO Abbreviation:  J Nutr Health Aging     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-22     Completed Date:  2010-10-14     Revised Date:  2011-01-05    
Medline Journal Info:
Nlm Unique ID:  100893366     Medline TA:  J Nutr Health Aging     Country:  France    
Other Details:
Languages:  eng     Pagination:  332-5     Citation Subset:  IM    
Nutrition and Foodborne Disease Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
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MeSH Terms
China / epidemiology
Diet Records
Diet Surveys
Heme / analysis
Hyperglycemia / blood,  epidemiology,  etiology*
Iron, Dietary / administration & dosage*
Micronutrients / administration & dosage*
Middle Aged
Odds Ratio
Prospective Studies
Reference Values
Risk Factors
Treatment Outcome
Zinc / administration & dosage*,  blood
Reg. No./Substance:
0/Iron, Dietary; 0/Micronutrients; 14875-96-8/Heme; 7440-66-6/Zinc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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