| Zebrafish teratogenicity testing. | |
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MedLine Citation:
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PMID: 23138918 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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As a model for teratogenicity research, zebrafish are gaining popularity and creditability. Zebrafish embryos have been proven to be a highly valuable tool in genetics and developmental biology research and have advanced our understanding of a number of known developmental toxicants. It has yet to be determined conclusively how reliably a zebrafish embryo screening assay predicts what will happen in mammalian models, but results from initial assessments have been encouraging. Here we have presented procedures for the basic care of a zebrafish colony to support embryo production, embryo collection and culturing, and teratogenicity experiments. |
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Authors:
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Kimberly C Brannen; Jeffrey H Charlap; Elise M Lewis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Methods in molecular biology (Clifton, N.J.) Volume: 947 ISSN: 1940-6029 ISO Abbreviation: Methods Mol. Biol. Publication Date: 2013 |
Date Detail:
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Created Date: 2012-11-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9214969 Medline TA: Methods Mol Biol Country: United States |
Other Details:
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Languages: eng Pagination: 383-401 Citation Subset: IM |
Affiliation:
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Charles River Laboratories, Horsham, PA, USA, Kimberly.Brannen@crl.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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