Document Detail


Zebrafish genetics gets the Scube on Hedgehog secretion.
MedLine Citation:
PMID:  23154980     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Inspired by a zebrafish mutation, two recent studies by Creanga and colleagues (pp. 1312-1325) and Tukachinsky and colleagues have shed new light on the way in which lipidated Hedgehog proteins are secreted and released from expressing cells, suggesting a model for the sequential action of the Disp and Scube2 proteins in this process.
Authors:
Philip W Ingham
Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Genes & development     Volume:  26     ISSN:  1549-5477     ISO Abbreviation:  Genes Dev.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-16     Completed Date:  2013-01-17     Revised Date:  2013-05-15    
Medline Journal Info:
Nlm Unique ID:  8711660     Medline TA:  Genes Dev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2468-70     Citation Subset:  -    
Affiliation:
Institute of Molecular and Cell Biology (IMCB), Singapore, Singapore.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Comments/Corrections
Comment On:
Genes Dev. 2012 Jun 15;26(12):1312-25   [PMID:  22677548 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Spliceosome activation: U4 is the path, stem I is the goal, and Prp8 is the keeper. Let's cheer for ...
Next Document:  The SMAD2/3 corepressor SNON maintains pluripotency through selective repression of mesendodermal ge...