Document Detail

Zebrafish genetics gets the Scube on Hedgehog secretion.
MedLine Citation:
PMID:  23154980     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Inspired by a zebrafish mutation, two recent studies by Creanga and colleagues (pp. 1312-1325) and Tukachinsky and colleagues have shed new light on the way in which lipidated Hedgehog proteins are secreted and released from expressing cells, suggesting a model for the sequential action of the Disp and Scube2 proteins in this process.
Philip W Ingham
Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Genes & development     Volume:  26     ISSN:  1549-5477     ISO Abbreviation:  Genes Dev.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-16     Completed Date:  2013-01-17     Revised Date:  2013-05-15    
Medline Journal Info:
Nlm Unique ID:  8711660     Medline TA:  Genes Dev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2468-70     Citation Subset:  -    
Institute of Molecular and Cell Biology (IMCB), Singapore, Singapore.
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MeSH Terms
Comment On:
Genes Dev. 2012 Jun 15;26(12):1312-25   [PMID:  22677548 ]

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