| Zebrafish Heart Regeneration as a Model for Cardiac Tissue Repair. | |
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MedLine Citation:
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PMID: 19081827 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Heart disease remains the leading cause of mortality throughout the world. Mammals have an extremely limited capacity to repair lost or damaged heart tissue, thus encouraging biologists to seek out models for heart regeneration. Zebrafish exhibit a robust regenerative capacity in a variety of tissues including the fin, spinal cord, retina, and heart, making it the sole regenerative vertebrate organism currently amenable to genetic manipulation. Future studies will utilize functional approaches to tease apart zebrafish heart regeneration in hopes of unlocking our own regenerative potential. |
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Authors:
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Robert J Major; Kenneth D Poss |
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Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Drug discovery today. Disease models Volume: 4 ISSN: 1740-6757 ISO Abbreviation: - Publication Date: 2007 |
Date Detail:
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Created Date: 2009-3-5 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101235079 Medline TA: Drug Discov Today Dis Models Country: - |
Other Details:
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Languages: ENG Pagination: 219-225 Citation Subset: - |
Affiliation:
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Department of Cell Biology, Duke University Medical Center, Durham, NC 27710 USA. |
Export Citation:
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Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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R01 HL081674-03//NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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