Document Detail


Young adult survivors of sudden cardiac arrest: analysis of invasive evaluation of 22 subjects.
MedLine Citation:
PMID:  2750649     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twenty-two young adult (mean age 27.8 +/- 5.3 years) survivors of sudden cardiac arrest underwent invasive cardiac assessment. Initial evaluation by cardiac catheterization, coronary angiography, and hemodynamic studies identified two groups of young survivors. The first consisted of 13 (60%) subjects who had definable structural cardiac or lung disease accountable for a cardiac arrest event. Dilated cardiomyopathy dominated this group. Mitral valve prolapse, hypertrophic cardiomyopathy, left ventricular hypertrophy, anomalous origin of the right coronary artery, and tetralogy of Fallot were also encountered. The second group included nine subjects (40%) with normal cardiac structure and normal hemodynamic parameters. Electrophysiologic testing demonstrated in three of these patients the presence of Wolff-Parkinson-White syndrome. The electrophysiologic studies had a higher yield in reproduction of life-threatening arrhythmias among the subjects in the second group as opposed to the first group. The observation that 10 subjects (45%) from both groups had preceding symptoms varying from palpitations and chest pain to syncope and recurrent cardiac arrest events, is in contradiction to previous findings in the literature and raises a question of appropriate evaluation of young adults with cardiac symptoms.
Authors:
O Topaz; E Perin; M Cox; S M Mallon; A Castellanos; R J Myerburg
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American heart journal     Volume:  118     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1989 Aug 
Date Detail:
Created Date:  1989-08-23     Completed Date:  1989-08-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  281-7     Citation Subset:  AIM; IM    
Affiliation:
Division of Cardiology, University of Miami School of Medicine, FL 33101.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Cardiac Pacing, Artificial
Coronary Angiography
Electrocardiography
Female
Heart / radiography
Heart Arrest / etiology,  physiopathology*
Heart Catheterization
Heart Diseases / diagnosis,  radiography
Hemodynamics
Humans
Male
Resuscitation
Grant Support
ID/Acronym/Agency:
HL-07436/HL/NHLBI NIH HHS; HL-28130/HL/NHLBI NIH HHS

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