| Yolk sac tumor in the fourth ventricle: a case report. | |
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MedLine Citation:
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PMID: 19540038 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The nongerminomatous germ cell tumor occurring in the fourth ventricle is extremely rare. A 9-year-old boy presented with symptoms of obvious headache, projectile vomiting, diplopia and motor weakness. MRI scanning revealed lesions occupying the fourth ventricle, with dual-lateral ventricle expansion after gadolinium administration. Suboccipital craniectomy was performed and the tumor was removed by block resection. Twice intraoperative biopsy specimens revealed fiber vascular tissue and hemangioma. Histological examination revealed that the tumor consisted of loose network structures and Schiller-Duval bodies. Immunohistochemical study showed that the primitive germ cells were positive for placental alkaline phosphatase, alpha-fetoprotein, cytokeratin, vimentin, but negative for glial fibrillary acidic protein. The histological diagnosis was pure yolk sac tumor. Two years after surgery, he has suffered no tumor recurrence. A combination of surgical treatment, radiation and chemotherapy is mandatory. |
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Authors:
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Cui Gaoyu; Guo Deyu; Chen Zhi; Feng Hua |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-06-21 |
Journal Detail:
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Title: Clinical neurology and neurosurgery Volume: 111 ISSN: 1872-6968 ISO Abbreviation: Clin Neurol Neurosurg Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-07-20 Completed Date: 2009-09-28 Revised Date: 2009-10-14 |
Medline Journal Info:
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Nlm Unique ID: 7502039 Medline TA: Clin Neurol Neurosurg Country: Netherlands |
Other Details:
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Languages: eng Pagination: 636-7 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing 40038, China. cgaoyu@sina.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Ventricle Neoplasms
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pathology*,
surgery,
therapy Child Combined Modality Therapy Drainage Endodermal Sinus Tumor / pathology*, surgery, therapy Humans Immunohistochemistry Magnetic Resonance Imaging Male Neurosurgical Procedures Third Ventricle / pathology*, surgery Tomography, X-Ray Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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