Document Detail


Yersinia enterocolitica: Mode of Transmission, Molecular Insights of Virulence, and Pathogenesis of Infection.
MedLine Citation:
PMID:  22567333     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Although Yersinia enterocolitica is usually transmitted through contaminated food and untreated water, occasional transmission such as human-to-human, animal-to-human and blood transfusion associated transmission have also identified in human disease. Of the six Y. enterocolitica biotypes, the virulence of the pathogenic biotypes, namely, 1B and 2-5 is attributed to the presence of a highly conserved 70-kb virulence plasmid, termed pYV/pCD and certain chromosomal genes. Some biotype 1A strains, despite lacking virulence plasmid (pYV) and traditional chromosomal virulence genes, are isolated frequently from humans with gastrointestinal diseases similar to that produced by isolates belonging known pathogenic biotypes. Y. enterocolitica pathogenic biotypes have evolved two major properties: the ability to penetrate the intestinal wall, which is thought to be controlled by plasmid genes, and the production of heat-stable enterotoxin, which is controlled by chromosomal genes.
Authors:
Yeasmin Sabina; Atiqur Rahman; Ramesh Chandra Ray; Didier Montet
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Publication Detail:
Type:  Journal Article     Date:  2011-09-07
Journal Detail:
Title:  Journal of pathogens     Volume:  2011     ISSN:  2090-3065     ISO Abbreviation:  J Pathog     Publication Date:  2011  
Date Detail:
Created Date:  2012-05-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101571433     Medline TA:  J Pathog     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  429069     Citation Subset:  -    
Affiliation:
Department of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka 1000, Bangladesh.
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