| Yeast mating: a model system for studying cell and nuclear fusion. | |
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MedLine Citation:
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PMID: 18979235 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Haploid yeast cells mate to form a zygote, whose progeny are diploid cells. A fundamentally sexual event, related to fertilization, yeast mating nevertheless exhibits cytological properties that appear similar to somatic cell fusion. A large collection of mutations that lead to defects in various stages of mating, including cell fusion, has allowed a detailed dissection of the overall pathway. Recent advances in imaging methods, together with powerful methods of genetic analysis, make yeast mating a superb platform for investigation of cell fusion. An understanding of yeast cell fusion will provide insight into fundamental mechanisms of cell signaling, cell polarization, and membrane fusion. |
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Authors:
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Casey A Ydenberg; Mark D Rose |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Methods in molecular biology (Clifton, N.J.) Volume: 475 ISSN: 1064-3745 ISO Abbreviation: Methods Mol. Biol. Publication Date: 2008 |
Date Detail:
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Created Date: 2008-11-03 Completed Date: 2008-11-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9214969 Medline TA: Methods Mol Biol Country: United States |
Other Details:
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Languages: eng Pagination: 3-20 Citation Subset: IM |
Affiliation:
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Department of Molecular Biology, Princeton University, Princeton, NJ, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cell Adhesion Cell Membrane / metabolism Cell Nucleus / metabolism* Cell Polarity Cell Wall / metabolism Membrane Fusion* Models, Biological* Pheromones / metabolism Reproduction Saccharomyces cerevisiae / cytology*, physiology Signal Transduction |
| Chemical | |
Reg. No./Substance:
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0/Pheromones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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