Document Detail

Yeast hydrolysate can reduce body weight and abdominal fat accumulation in obese adults.
MedLine Citation:
PMID:  24290594     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: The aim of this study was to examine the effect of yeast hydrolysate on the abdominal fat in obese humans.
METHODS: We observed the effects of yeast hydrolysate that had a molecular weight below 10 kDa on the anti-abdominal fat accumulation in obese men and women ages 20 to 50 y for 10 wk. The abdominal fat mass was assessed by computed tomographic scans.
RESULTS: By the sixth week, the reductions in energy intake in the yeast group (yeast hydrolysate 1 g/d) were significantly greater than those in the control group (placebo 1 g/d) (P < 0.05). The body weight and body mass index (BMI) were significantly reduced by week 10 compared with baseline in the yeast group, and these differences were significantly greater than those in the control group: body weight 0.83 kg versus -2.60 k g (P < 0.001), BMI 0.29 kg/m(2) versus -0.90 kg/m(2) (P < 0.001). Despite the increased loss of body weight in the yeast group, lean body mass did not significantly differ between the two groups. Body fat mass in the control group did not significantly change between baseline and week 10. However, the yeast group lost a significant amount of body fat mass after 10 wk of treatment (P < 0.01). The differences in abdominal fat thickness and abdominal circumference between the two groups were significant after 10 wk of treatment (P < 0.001). The total abdominal fat area in the yeast group was significantly lower than in the control group after 10 wk of treatment (-7.06 cm(2) versus -17.34 cm(2); P < 0.01).
CONCLUSIONS: Yeast hydrolysate can reduce body weight and the accumulation of abdominal fat without an adverse effect on lean body mass in obese adults, regardless of sex, via the reduction of energy intake.
Eun Young Jung; Mi Kyoung Cho; Yang-Hee Hong; Jae Hwan Kim; Yooheon Park; Un Jae Chang; Hyung Joo Suh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nutrition (Burbank, Los Angeles County, Calif.)     Volume:  30     ISSN:  1873-1244     ISO Abbreviation:  Nutrition     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2013-12-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8802712     Medline TA:  Nutrition     Country:  United States    
Other Details:
Languages:  eng     Pagination:  25-32     Citation Subset:  IM    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
Department of Home Economic Education, Jeonju University, Jeonju, Republic of Korea.
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