| Yak lactate dehydgogenase A4: purification, properties, and cDNA cloning. | |
| | |
MedLine Citation:
|
PMID: 18776664 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Lactate dehydrogenase A4 (LDH-A4) was purified for yak skeletal muscle. Michaelis constant (Km) analysis showed that yak LDH-A4 for pyruvate was significantly higher than that of cattle. cDNA cloning of LDH-A revealed two amino acid substitutions between yak and cattle. We suggest that the higher Km of yak LDH-A4 might be a result of molecular adaptation to a hypoxic environment. |
| | |
Authors:
|
Yucai Zheng; Xiaohui Si; Qinghua He; Suyu Jin; Jian Hong |
Related Documents
:
|
1372864 - Reaction of adrenal glomerular zone to detergents. 2033454 - Prevention of cerebral vasospasm by actinomycin d. 10791804 - Invited review: effects of diet shifts on escherichia coli in cattle. 16345284 - Double-stranded ribonucleic acid in viruses of penicillium citrinum. 12350144 - Oxidation, reduction, and methylation of carnosic acid by nocardia. 16657654 - Bicarbonate fixation and malate compartmentation in relation to salt-induced stoichiome... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-09-07 |
Journal Detail:
|
Title: Bioscience, biotechnology, and biochemistry Volume: 72 ISSN: 1347-6947 ISO Abbreviation: Biosci. Biotechnol. Biochem. Publication Date: 2008 Sep |
Date Detail:
|
Created Date: 2008-09-24 Completed Date: 2008-12-18 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9205717 Medline TA: Biosci Biotechnol Biochem Country: Japan |
Other Details:
|
Languages: eng Pagination: 2448-51 Citation Subset: IM |
Affiliation:
|
College of Life Science and Technology, Southwest University for Nationalities, Chengdu, PR China. yucaizheng01@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Amino Acid Sequence Amino Acid Substitution Animals Cattle / genetics* Cloning, Molecular DNA, Complementary / genetics, isolation & purification Isoenzymes / genetics*, metabolism* Kinetics L-Lactate Dehydrogenase / genetics*, isolation & purification*, metabolism Lactic Acid / isolation & purification Models, Molecular Molecular Sequence Data Muscle, Skeletal / enzymology Pyruvic Acid / isolation & purification Sequence Homology, Amino Acid |
| Chemical | |
Reg. No./Substance:
|
0/DNA, Complementary; 0/Isoenzymes; 127-17-3/Pyruvic Acid; 50-21-5/Lactic Acid; EC 1.1.1.27/L-Lactate Dehydrogenase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Extract from Acanthopanax senticosus harms (Siberian ginseng) activates NTS and SON/PVN in the rat b...
Next Document: The effects of NaCl on lipid peroxidation-derived aldehyde, 4-hydroxy-2-hexenal formation in boiled ...