| Yacon syrup: beneficial effects on obesity and insulin resistance in humans. | |
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MedLine Citation:
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PMID: 19254816 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND & AIMS: Syrup obtained from yacon roots could be well positioned as a nutraceutical product due to its high fructooligosaccharides content. We examined the beneficial effects and tolerance of yacon syrup on human health. METHODS: Obese and slightly dyslipidemic pre-menopausal women were studied over a 120-day period in a double-blind placebo-controlled experiment. We used two doses of yacon syrup, 0.29 g and 0.14 g fructooligosaccharides/kg/day. At the start and end of the study, anthropometric measurements, blood glucose, calcium, lipid and insulin concentrations and Homeostasis Model Assessment index were determined. RESULTS: The recommended daily consumption of yacon syrup with no undesirable gastrointestinal effects is 0.14 g fructooligosaccharides/kg. Daily intake of yacon syrup produced a significant decrease in body weight, waist circumference and body mass index. Additionally, decrease in fasting serum insulin and Homeostasis Model Assessment index was observed. The consumption of yacon syrup increased defecation frequency and satiety sensation. Fasting glucose and serum lipids were not affected by syrup treatment and the only positive effect was found in serum LDL-cholesterol levels. CONCLUSIONS: Yacon syrup is a good source of fructooligosaccharides and its long-term consumption produced beneficial health effects on obese pre-menopausal women with insulin resistance. |
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Authors:
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Susana Genta; Wilfredo Cabrera; Natalia Habib; Juan Pons; Iván Manrique Carillo; Alfredo Grau; Sara Sánchez |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2009-02-28 |
Journal Detail:
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Title: Clinical nutrition (Edinburgh, Scotland) Volume: 28 ISSN: 1532-1983 ISO Abbreviation: Clin Nutr Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-04-10 Completed Date: 2009-08-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309603 Medline TA: Clin Nutr Country: England |
Other Details:
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Languages: eng Pagination: 182-7 Citation Subset: IM |
Affiliation:
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Instituto Superior de Investigaciones Biológicas, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de Tucumán, Chacabuco 461, 4000-San Miguel de Tucumán, Tucumán, Argentina. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anthropometry Blood Glucose / drug effects Body Mass Index Body Weight / drug effects Calcium / blood Dose-Response Relationship, Drug Double-Blind Method Dyslipidemias / diet therapy Female Humans Insulin / blood Insulin Resistance* Lipids / blood Middle Aged Obesity / diet therapy* Plant Extracts / administration & dosage* Plant Preparations / pharmacology* Satiety Response / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Lipids; 0/Plant Extracts; 0/Plant Preparations; 0/yacon syrup; 11061-68-0/Insulin; 7440-70-2/Calcium |
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