Document Detail

Y chromosome microdeletion screening in infertile men in France: a survey of French practice based on 88 IVF centres.
MedLine Citation:
PMID:  15033947     Owner:  NLM     Status:  MEDLINE    
Y chromosome microdeletion screening is advised in cases of severely impaired spermatogenesis. Improvements in molecular biological techniques have made diagnosis more accessible in routine analysis. However, Y chromosome microdeletions are not diagnosed in all IVF centres. The aim of the present study was to determine the regulatory (indications, financing) and performance (methods, invoicing) conditions required for this analysis, in France. Microdeletion detection was found to be spreading fast and consistantly. It therefore seems necessary for a consensus to be reached on indications, with a view to a standardized technique, with a common effort of experts in the field. Financial management by the French Health Insurance bodies (Sécurité Sociale) would be an essential step towards routine adoption. Lastly, the answers to our questionnaire revealed a strong demand for information concerning this analysis.
Isabelle Esther Aknin-Seifer; Hervé Lejeune; Renaud Laurian Touraine; Rachel Levy;
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Publication Detail:
Type:  Journal Article; Multicenter Study; Review     Date:  2004-02-12
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  19     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-03-22     Completed Date:  2004-11-09     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  England    
Other Details:
Languages:  eng     Pagination:  788-93     Citation Subset:  IM    
Laboratoire de Biologie de la Reproduction, Hôpital Nord, 42055 Saint Etienne, Lyon, France.
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MeSH Terms
Ambulatory Care Facilities*
Chromosomes, Human, Y*
Fertilization in Vitro*
Gene Deletion*
Genetic Testing*
Infertility, Male / genetics*
Professional Practice*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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