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XY FEMALES DO BETTER THAN THE XX IN THE AFRICAN PYGMY MOUSE, MUS MINUTOIDES.
MedLine Citation:
PMID:  24611447     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
All therian mammals have a similar XY/XX sex determination system except for a dozen species. The African pygmy mouse, Mus minutoides, harbors an unconventional system in which all males are XY, and there are three types of females: the usual XX but also XX* and X*Y ones (the asterisk designates a sex reversal mutation on the X chromosome). The long-term evolution of such a system is a paradox, since X*Y females are expected to face high reproductive costs (e.g. meiotic disruption and loss of unviable YY embryos), which should prevent invasion and maintenance of a sex-reversal mutation. Hence, mechanisms for compensating for the costs could have evolved in M. minutoides. Data gathered from our laboratory colony revealed that X*Y females do compensate and even show enhanced reproductive performance in comparison to the XX and XX*; they produce significantly more offspring due to (i) a higher probability of breeding, (ii) an earlier first litter, and (iii) a larger litter size, linked to (iv) a greater ovulation rate. These findings confirm that rare conditions are needed for an atypical sex determination mechanism to evolve in mammals, and provide valuable insight into understanding modifications of systems with highly heteromorphic sex chromosomes. This article is protected by copyright. All rights reserved.
Authors:
Paul A Saunders; Julie Perez; Massilva Rahmoun; Ophélie Ronce; Pierre-André Crochet; Frédéric Veyrunes
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-2-24
Journal Detail:
Title:  Evolution; international journal of organic evolution     Volume:  -     ISSN:  1558-5646     ISO Abbreviation:  Evolution     Publication Date:  2014 Feb 
Date Detail:
Created Date:  2014-3-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373224     Medline TA:  Evolution     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
This article is protected by copyright. All rights reserved.
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