Document Detail

Xstir polymorphism and absence of sex linkage in Xenopus laevis ME2 gene.
MedLine Citation:
PMID:  12859020     Owner:  NLM     Status:  MEDLINE    
A fragment of ME2 cDNA from exon 2 to exon 11 was sequenced and the sequence submitted to GenBank. Analysis of the intron, probably intron 13, revealed a polymorphism which is due to the presence of tandem repetitions of Xstir elements. Genetic analysis of the parents and the offspring showed a standard distribution of intron variants. This distribution was not dependent on sex. We conclude, contrary to previous reports, that the ME2 gene is not linked to sex. Consequently, the Xstir polymorphism can be used as a tool for genetic analysis.
J Mácha; T Tlapáková; V Krylov; V Kopský
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Folia biologica     Volume:  49     ISSN:  0015-5500     ISO Abbreviation:  Folia Biol. (Praha)     Publication Date:  2003  
Date Detail:
Created Date:  2003-07-15     Completed Date:  2004-03-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0234640     Medline TA:  Folia Biol (Praha)     Country:  Czech Republic    
Other Details:
Languages:  eng     Pagination:  115-7     Citation Subset:  IM    
Department of Animal Physiology and Developmental Biology, Faculty of Science, Charles University, Prague, Czech Republic.
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MeSH Terms
Amino Acid Sequence
Base Sequence
DNA, Complementary / metabolism
Genetic Markers
Linkage (Genetics)
Malate Dehydrogenase / genetics*
Molecular Sequence Data
Polymorphism, Genetic*
Reverse Transcriptase Polymerase Chain Reaction
Sequence Homology, Amino Acid
Sex Factors
Xenopus laevis / genetics*
Reg. No./Substance:
0/DNA, Complementary; 0/Genetic Markers; EC Dehydrogenase; EC dehydrogenase (decarboxylating)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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