Document Detail


Xerostomia in patients with triple A syndrome--a newly recognised finding.
MedLine Citation:
PMID:  11131343     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Triple A syndrome is characterised by achalasia, alacrima, adrenal insufficiency and progressive neurological abnormalities including impaired autonomic nervous function. We present five patients with triple A syndrome in whom we describe xerostomia for the first time, a symptom which was presumed to be practically exclusive to Sjøgren syndrome and familial dysautonomia. Conclusion We recommend the investigation of salivation in all patients with triple A syndrome and treatment of xerostomia in order to ease swallowing. Further, our results corroborate earlier doubts that some patients with Sjøgren syndrome, especially those with the so-called "achalasia sicca" syndrome and adrenocortical insufficiency, actually had triple A syndrome. Therefore, adrenocortical function should be assessed in all patients with Sjøgren syndrome, particularly in those with difficulties in swallowing, because even latent adrenocortical insufficiency could be life-threatening for these patients in stressful situations.
Authors:
M Dumić; M Mravak-Stipetić; Z Kaić; J Ille; V Plavsić; S Batinica; M Cvitanović
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of pediatrics     Volume:  159     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2000-12-22     Completed Date:  2001-02-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  885-8     Citation Subset:  IM    
Affiliation:
Department of Paediatrics, University Hospital Zagreb-Rebro, Croatia. maricvit@mef.hr
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adrenal Gland Diseases / complications*
Adult
Child
Esophageal Achalasia / complications*
Female
Humans
Lacrimal Apparatus Diseases / complications*
Syndrome
Xerostomia / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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