Document Detail

Xeroradiographic determination of Achilles tendon thickness in familial hypercholesterolemia confirmed by tissue cultures.
MedLine Citation:
PMID:  6838697     Owner:  NLM     Status:  MEDLINE    
Twenty-three patients with familial hypercholesterolemia (FHC) confirmed by tissue cultures of skin fibroblasts (2 homozygotes, 21 heterozygotes) and 3 patients with sporadic hypercholesterolemia were evaluated for Achilles tendon (AT) thickness by xeroradiography. Both homozygotes had thick ATs and coronary heart disease (CHD), 20 heterozygotes had thick ATs, but only 8 of them had CHD. One heterozygote had a small AT value, but CHD for a long time. The 3 patients with sporadic hypercholesterolemia, one with CHD, had small AT. There was no correlation between serum cholesterol concentration and AT thickness, between age and AT thickness, nor between AT thickness and CHD.
O Seidl; C Keller; H Berger; G Wolfram; N Zöllner
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Atherosclerosis     Volume:  46     ISSN:  0021-9150     ISO Abbreviation:  Atherosclerosis     Publication Date:  1983 Feb 
Date Detail:
Created Date:  1983-05-05     Completed Date:  1983-05-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0242543     Medline TA:  Atherosclerosis     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  163-72     Citation Subset:  IM    
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MeSH Terms
Achilles Tendon / pathology*
Age Factors
Coronary Disease / diagnosis,  pathology*
Hyperlipoproteinemia Type II / diagnosis,  pathology*
Middle Aged
Xanthomatosis / etiology,  pathology

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