Document Detail


Xanthomonas maltophilia bacteremia: an analysis of 32 cases.
MedLine Citation:
PMID:  1363639     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thirty-two cases of Xanthomonas maltophilia bacteremia have been identified over the last two years at the Veterans General Hospital, Taipei. Among them, 27 cases (84%) were due to hospital-acquired infections, and 14 cases (44%) were polymicrobial bacteremia. One case was confirmed as prosthetic valve endocarditis and one case was complicated by recurrent attacks of ecthyma gangrenosum. Most cases had severe debilitating conditions. Twelve cases (38%) had a malignancy, 19 cases (59%) were resident in the Intensive Care Unit and 16 cases (50%) had undergone major surgery. The main predisposing factors included central venous catheterization, endotracheal intubation or tracheostomy, prior antibiotic therapy and prolonged hospitalization. Moxalactam, chloramphenicol and trimethoprim-sulfamethoxazole were the most effective agents in vitro against X. maltophilia. Twenty-two cases (69%) died during hospitalization; 13 cases (41%) were directly attributed to septicemia. Factors that adversely influenced mortality included inappropriate antimicrobial therapy and prior antibiotic treatment. Of particular interest is the fact that none of the patients who did not receive appropriate antimicrobial therapy survived. Early diagnosis and appropriate antibiotic therapy are critical for improving the prognosis of X. maltophilia infection.
Authors:
T N Jang; F D Wang; L S Wang; C Y Liu; I M Liu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the Formosan Medical Association = Taiwan yi zhi     Volume:  91     ISSN:  0929-6646     ISO Abbreviation:  J. Formos. Med. Assoc.     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-05-04     Completed Date:  1993-05-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9214933     Medline TA:  J Formos Med Assoc     Country:  HONG KONG    
Other Details:
Languages:  eng     Pagination:  1170-6     Citation Subset:  IM    
Affiliation:
Department of Medicine, National Yang-Ming Medical College, Taipei, Taiwan, R.O.C.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Bacteremia / drug therapy,  etiology*
Cross Infection / etiology
Drug Resistance, Microbial
Female
Humans
Male
Middle Aged
Retrospective Studies
Trimethoprim-Sulfamethoxazole Combination / therapeutic use
Xanthomonas / drug effects,  isolation & purification*
Chemical
Reg. No./Substance:
8064-90-2/Trimethoprim-Sulfamethoxazole Combination

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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