Document Detail


Xanthoma disseminatum. An unusual histiocytosis syndrome.
MedLine Citation:
PMID:  3140686     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The histiocytoses are a diverse group of illnesses that present a variety of diagnostic and therapeutic dilemmas. In this article, we describe the case of an 8-year-old boy with xanthoma disseminatum, a histiocytic disorder involving the skin, eyes, and brain. In our discussion, we have emphasized the clinical, pathologic, and radiographic features that distinguish this entity from clinically similar juvenile xanthogranuloma and Langerhans' cell histiocytoses (histiocytosis X) such as the Hand-Schuller-Christian syndrome. The importance of differentiating the various histiocytoses, in view of their varying natural histories and therapeutic responsiveness, is reviewed in relation to the new classification system for these disorders proposed by the Histiocyte Society.
Authors:
R H Giller; R Folberg; R V Keech; W W Piette; Y Sato
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of pediatric hematology/oncology     Volume:  10     ISSN:  0192-8562     ISO Abbreviation:  Am J Pediatr Hematol Oncol     Publication Date:  1988  
Date Detail:
Created Date:  1988-11-16     Completed Date:  1988-11-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7908071     Medline TA:  Am J Pediatr Hematol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  252-7     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Iowa College of Medicine, Iowa City.
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MeSH Terms
Descriptor/Qualifier:
Brain Diseases / diagnosis
Child
Diagnosis, Differential
Eye Diseases / diagnosis
Histiocytosis, Langerhans-Cell / diagnosis
Humans
Male
Syndrome
Xanthogranuloma, Juvenile / diagnosis
Xanthomatosis / classification,  diagnosis*

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