Document Detail

Xanthoma disseminatum: case report.
MedLine Citation:
PMID:  15588563     Owner:  NLM     Status:  MEDLINE    
Xanthoma disseminatum is a rare, benign, non-Langerhans' cell histiocytic disorder of unknown etiology. A case is presented of a 71-year-old man with a three-year history of disseminated symmetric yellowish papules and plaques on the skin of the face, neck, flexor regions, trunk, extremities and oral mucosa, with fatty infiltration of the liver and pancreas, and cardiac complaints. Xanthomatous rhinophyma predominated on the face. Clinical, immunohistochemistry and histology findings indicated the diagnosis of xanthoma disseminatum. Although the patient had a positive family history of cardiovascular diseases and a number of symptoms that are often associated with hyperlipidemia, repeat plasma levels were always within the normal limits. The case was interesting because of a number of etiologic factors that could be connected with the appearance of xanthomas in our patient. Therefore it was difficult to classify the disease into one of well-defined nosologic entities. The case report is supplemented with a review of relevant literature.
Dijana Celić; Jaka Rados; Jasna Lipozencić; Ivan Dobrić
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Acta dermatovenerologica Croatica : ADC     Volume:  12     ISSN:  1330-027X     ISO Abbreviation:  Acta Dermatovenerol Croat     Publication Date:  2004  
Date Detail:
Created Date:  2004-12-13     Completed Date:  2005-04-12     Revised Date:  2011-09-13    
Medline Journal Info:
Nlm Unique ID:  9433781     Medline TA:  Acta Dermatovenerol Croat     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  282-8     Citation Subset:  IM    
Medikol Outpatient Department, Zagreb University Medical Center, Dobri dol 49, 10000 Zagreb, Croatia.
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MeSH Terms
Histiocytosis, Non-Langerhans-Cell / pathology*

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