Document Detail

Xanthogranuloma of the sellar region.
MedLine Citation:
PMID:  16341628     Owner:  NLM     Status:  MEDLINE    
The incidence of diagnosed xanthogranuloma of the sellar region is very low [1, 2, 5, 6]. We report about two cases 1) in a 57-year-old female and 2) in a 5-year-old boy. In both cases radiographic findings revealed an inhomogeneous, contrast enhancing sellar lesion. Histopathology showed the typical features of a xanthogranuloma of the sellar region with cholesterol clefts, lympho-plasmacellular infiltrates, marked hemosiderin deposits, multinucleated foreign body giant cells around cholesterol clefts, accumulation of macrophages and only small epithelial cell clusters [6]. As xanthogranuloma of the sellar region are rarely diagnosed we want to draw attention to this rather unusual diagnosis.
C S Jung; A Schänzer; E Hattingen; K H Plate; V Seifert
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2005-12-12
Journal Detail:
Title:  Acta neurochirurgica     Volume:  148     ISSN:  0001-6268     ISO Abbreviation:  Acta Neurochir (Wien)     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-03-20     Completed Date:  2006-08-31     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0151000     Medline TA:  Acta Neurochir (Wien)     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  473-7     Citation Subset:  IM    
Department of Neurosurgery, Johann-Wolfgang Goethe University Frankfurt, Frankfurt, Germany.
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MeSH Terms
Child, Preschool
Cholesterol / metabolism
Craniopharyngioma / diagnosis
Diagnosis, Differential
Giant Cells, Foreign-Body / pathology
Hemosiderin / metabolism
Hypopituitarism / etiology,  physiopathology,  surgery
Lymphocytes / pathology
Macrophages / pathology
Middle Aged
Neurosurgical Procedures
Pituitary Gland / pathology*,  physiopathology,  surgery
Postoperative Complications / etiology,  physiopathology,  therapy
Sella Turcica / pathology*,  physiopathology,  surgery
Skull Base Neoplasms / diagnosis*,  physiopathology*,  surgery
Treatment Outcome
Xanthogranuloma, Juvenile / diagnosis*,  physiopathology*,  surgery
Reg. No./Substance:
57-88-5/Cholesterol; 9011-92-1/Hemosiderin

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