Document Detail


Xanthine oxidase, an indicator of secretory differentiation in mammary cells.
MedLine Citation:
PMID:  6688588     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Elevated levels of xanthine oxidase were found in (1) lactating mouse mammary glands, compared with virgin and midpregnant glands; and (2) primary mouse mammary cells cultured on floating collagen gels, compared with non-secretory cells on attached gels. In primary culture, increase in xanthine oxidase activity above a basal level coincided with secretory activity as measured by casein production; intracellular levels of casein and xanthine oxidase showed a high degree of correspondence. It is suggested that xanthine oxidase levels can be used as an indicator of in vivo and in vitro secretory differentiation in mammary epithelial cells.
Authors:
D L Ringo; V Rocha
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Experimental cell research     Volume:  147     ISSN:  0014-4827     ISO Abbreviation:  Exp. Cell Res.     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0373226     Medline TA:  Exp Cell Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  216-20     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Differentiation
Female
Lactation
Mammary Glands, Animal / cytology*,  enzymology
Mice
Mice, Inbred BALB C
Pregnancy
Pregnancy, Animal
Xanthine Oxidase / analysis*
Grant Support
ID/Acronym/Agency:
RR08132/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
EC 1.17.3.2/Xanthine Oxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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