Document Detail

Xanthine oxidase in critically ischaemic and claudicant limbs: profile of activity during early reperfusion.
MedLine Citation:
PMID:  8696745     Owner:  NLM     Status:  MEDLINE    
Xanthine oxidase activity in blood from the ipsilateral femoral vein, and the relationship between xanthine oxidase production and the products of lipid peroxidation, were studied before operation and for 60 min following release of clamps after successful revascularization in two groups of patients with claudication or critical ischaemia. Before revascularization, detectable levels of xanthine oxidase were found only in patients with critical ischaemia. Clamping during bypass surgery led to release of xanthine oxidase in claudicants, but this activity reduced after 60 min. There was no evidence of lipid peroxidation during this time. Xanthine oxidase activity in brachial vein blood was higher than in femoral vein blood in patients with critical ischaemia before revascularization.
A L Trewick; K el-Hassan; J M Round; M Adiseshiah
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  83     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1996-09-05     Completed Date:  1996-09-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  798-802     Citation Subset:  AIM; IM    
Department of Chemical Pathology, University College London Hospitals, UK.
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MeSH Terms
Aged, 80 and over
Femoral Vein
Intermittent Claudication / enzymology*
Ischemia / enzymology*
Leg / blood supply*
Middle Aged
Xanthine Oxidase / metabolism*
Reg. No./Substance:
EC Oxidase

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