Document Detail

Is XMRV a causal virus for prostate cancer?
MedLine Citation:
PMID:  21765437     Owner:  NLM     Status:  MEDLINE    
The potential association between xenotropic murine leukaemia virus-related gammaretrovirus (XMRV) and prostate cancer (PCa) has been documented since 2006. It is important for furthering our understanding of the biological mechanisms of PCa to ascertain whether this association is causal. To summarize the available information on the epidemiological and laboratory findings of the association, we conducted a literature search of the PubMed electronic database (from March 2006 to February 2011) to identify relevant published studies that examined the association between XMRV and PCa. Although several studies showed the positive association between XMRV and PCa, more recent studies did not support this conclusion. The positive findings might be due to contamination of human samples. Further studies are needed to clarify this association.
Zhen-Zhen Zhang; Bao-Feng Guo; Zhuang Feng; Ling Zhang; Xue-Jian Zhao
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2011-07-18
Journal Detail:
Title:  Asian journal of andrology     Volume:  13     ISSN:  1745-7262     ISO Abbreviation:  Asian J. Androl.     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-05     Completed Date:  2011-12-27     Revised Date:  2013-09-17    
Medline Journal Info:
Nlm Unique ID:  100942132     Medline TA:  Asian J Androl     Country:  China    
Other Details:
Languages:  eng     Pagination:  698-701     Citation Subset:  IM    
Department of Epidemiology, Michigan State University, East Lansing, MI 48224, USA.
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MeSH Terms
Fatigue Syndrome, Chronic / virology
Prostatic Neoplasms / virology*
Xenotropic murine leukemia virus-related virus / pathogenicity*

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