Document Detail


X-ray microprobe analysis of Michaelis-Gutmann bodies in human and experimental malakoplakia.
MedLine Citation:
PMID:  623208     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Using x-ray microprobe analysis, we studied Michaelis-Gutmann bodies (M-G bodies) in malakoplakia tissue samples from human kidney and testis as well as from lesions experimentally induced in the rat. In all the M-G bodies tested we could unambiguously detect calcium at both its Kalpha and Kbeta lines. The actual amount of calcium depended on the developmental state, ie, on the degree of calcification of the M-G body, In M-G bodies of rat kidney malakoplakia tissue fixed without osmium tetroxide, the phosphorus could also be detected unambigously. From the ratios of calcium and phosphorus percentages (w/w) we concluded that CaHPO4 was present. No difference was found between M-G bodies in malakoplakia tissues of human origin and those in experimentally induced malakoplakia.
Authors:
E Kuthy; J Ormos
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of pathology     Volume:  90     ISSN:  0002-9440     ISO Abbreviation:  Am. J. Pathol.     Publication Date:  1978 Feb 
Date Detail:
Created Date:  1978-03-21     Completed Date:  1978-03-21     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370502     Medline TA:  Am J Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  411-22     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Calcium / analysis,  metabolism*
Electron Probe Microanalysis
Histocytochemistry
Humans
Kidney / chemistry,  ultrastructure*
Kidney Diseases / metabolism*
Malacoplakia / metabolism*
Male
Methods
Microbodies / metabolism*
Organoids / metabolism*
Phosphorus / analysis,  metabolism*
Rats
Testicular Diseases / metabolism*
Testis / chemistry,  ultrastructure*
Chemical
Reg. No./Substance:
7440-70-2/Calcium; 7723-14-0/Phosphorus
Comments/Corrections

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