Document Detail


X-ray spectroscopic observation of an interstitial carbide in NifEN-bound FeMoco precursor.
MedLine Citation:
PMID:  23276198     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The iron-molybdenum cofactor (FeMoco) of nitrogenase contains a biologically unprecedented μ(6)-coordinated C(4-) ion. Although the role of this interstitial atom in nitrogenase catalysis is unknown, progress in understanding its biosynthetic origins has been made. Here we report valence-to-core Fe Kβ X-ray emission spectroscopy data to show that this C(4-) ion is present in the Fe(8)S(9) "L-cluster," which is the immediate precursor to FeMoco prior to the insertion of molybdenum and coordination by homocitrate. These results accord with recent evidence supporting a role for the S-adenosylmethionine-dependent enzyme NifB in the incorporation of carbon into the FeMoco center of nitrogenase.
Authors:
Kyle M Lancaster; Yilin Hu; Uwe Bergmann; Markus W Ribbe; Serena DeBeer
Related Documents :
24387288 - A new layered iron arsenide superconductor: (ca,pr)feas2.
22905018 - 2,7-dimeth-oxy-1-(2-naphtho-yl)naph-thalene.
25076058 - Development of pd-cu/hematite catalyst for selective nitrate reduction.
188128 - High-field 13c nmr studies of certain normal and abnormal human plasma lipoproteins.
24292358 - Structure-property studies of thermoplastic and thermosetting polyurethanes using palm ...
23168338 - Anisotropic fatigue behavior of human enamel characterized by multi-cycling nanoindenta...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2013-01-08
Journal Detail:
Title:  Journal of the American Chemical Society     Volume:  135     ISSN:  1520-5126     ISO Abbreviation:  J. Am. Chem. Soc.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-16     Completed Date:  2013-06-19     Revised Date:  2014-01-23    
Medline Journal Info:
Nlm Unique ID:  7503056     Medline TA:  J Am Chem Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  610-2     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Iron Compounds / chemistry*,  metabolism
Molecular Structure
Molybdoferredoxin / chemistry*,  metabolism
Spectrometry, X-Ray Emission
Tricarboxylic Acids / chemistry
Grant Support
ID/Acronym/Agency:
R01 GM067626/GM/NIGMS NIH HHS; R01GM67626/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Iron Compounds; 0/Molybdoferredoxin; 0/NifB cofactor; 0/Tricarboxylic Acids; 3562-74-1/homocitric acid
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Presenteeism and Absenteeism: Differentiated Understanding of Related Phenomena.
Next Document:  Pain when walking: individual sensory profiles in the foot soles of torture victims - a controlled s...